What is Necrotic Enteritis (NE)?
Necrotic Enteritis (NE) is a bacterial disease that is caused by Clostridium perfringenes organisms. It is the most devastating disease for poultry due to the huge economic impact of around 6-7 billion us dollars globally.
Necrotic Enteritis always occurred with coccidiosis (Emeria acervulina & Emeria mitis)hat are most confusing in the field.
Its gram-positive, rod-shaped, obligate anaerobic organism. Its ferment glucose, fructose, sucrose, etc.
There are five types A, B, C, D, E which producing several toxins like alpha, gamma, beta, epsilon, etc C.perfringenes. Types A & C only responsible for causing Necrotic Enteritis & enterotoxemia in poultry.
C.perfringenes ubiquitous that is normal inhabitant at the intestinal tract of poultry, soil, litter, etc,
As necrotic Enteritis caused by the gram-positive bacteria, it is the most sensitive to penicillin types antibiotics. The normal penicillin types of antibiotics types drugs are Amoxycillin, ampicillin, carbenicillin, ticarcillin, and piperacillin, amoxicillin, nafcillin, oxacillin, dicloxacillin, flucloxacillin, and others such as lincomycin.
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It is always associated with intestinal coccidia called Emeria acervulina. maxima and others. to treat coccidial infection, using gut active sulphonamide such as sulphaclozine sodium, sulphadimidine, sulphadiazine along with potentiated sulphonamide, etc.