Anti-coccidial for coccidiosis
Anti-coccidial for coccidiosis is an easy task for poultry. Because coccidiosis, a is life term disease of poultry is a normal inhabitant in the intestine. If we know, Ultimate anti-coccidial drugs and their mode of action, it is a cure at a short stages Coccidiosis treatment is a similar event to continue long term up to marketing age.
Types of coccidiosis treatment
Coccidiosis treatment is given in two ways in the field. Drugs provide by the feed and the second option is water. Today we discuss the top 3 anticoccidial drugs which provide by water.
Diclazuril is an Anti-coccidial drug and it is a member of the triazine class, which is chemically similar to ponazuril. Despite acts on all Emeria species, it is also active in the Isospora app, Toxoplasma Gondi.
Mode of Action
The exact mode of action is still unknown. But, diclazuril exerts his antics neuronal effect by inhibiting merozoite production. It mainly functions on the sexual life cycle of the Emeria app and breaks its life and stops the proliferation of the Emeria app.
Dosages and Administration
Dosage of diclazuril varies from age to age and its dosage range from 1-50 mg/ kg body weight.
Diclazuril found as an oral solution that contains diclazuril 10% and available for oral medication.
Diclazuril is the safest anticoccidial drugs die to it can use all ages in poultry. It can give day 01- up to market age. There is no complication or contradiction with other drugs. There is a record of weight loss and other adverse effects of diclazuril in the field study.
2. Suphaclozine sodium
Suphaclozine sodium is white, crystalline, free-flowing water-soluble powder. It is active against all types of protozoan species especially Emeria app and certain types of bacteria.
Mode of action
It is an antibiotic belong to a group of sulphonamide. Like another sulphonamide, it is an antagonist of para-aminobenzoic acid, a precursor of folic acid in protozoa and bacteria. Folic acid is a coenzyme necessary for the synthesis of nucleic acid. By which, protozoa and bacteria don’t multiply in the presence of suphaclozine sodium.
There are two types of formulation available in the market 30% and 60% which available in powder form.
The dose of suphaclozine sodium varies to which types of coccidia infect and causing coccidiosis in poultry.
In the case of, Eimeria tenella and Emeria nicartrix dosage start from 75-100 mg/ day and corresponding to 140-190 mg/ kg/day
Except both this species, Dosing start from 50 mg/ kg/ day corresponding to 90 mg/kg / day.
Toltrazuril is an anticoccidial, coccidiostat drug derived from triazinetrione derivatives and a potent drug for treating coccidiosis in poultry.
Mode of action
Toltrazuril is active against all intracellular development stages including schizonts, micro, and macrogamonts. It inhibits the division of the protozoal nucleus, the activity of the mitochondria, and damages the wall forming bodies in the microgametes. of Eimeria spp.That’s why Toltrazuril shows coccidial rather than coccidiostats action.
Dosage and Administration
For the treatment of coccidiosis, Totrazuril gives at 7 mg/kg body weight or 1ml/liter of drinking water or 28 ml/100 kg flocks for 2 consecutive days; 24 hours continuously or 8 hours each day in drinking water.
In severe infections, the treatment may be repeated 5 days later.
Prevention of coccidiosis- 7 mg/kg bodyweight for 2 consecutive days within 10-18 days per month up to 4 months of age as a strategic administration program. Or as directed by the registered Veterinarian.
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