Anticoccidial defined as an antiprotozoal agent used for the prevention & control of coccidiosis is called Anticoccidial. these drugs either be Coccidiostat or Coccidiocidal agents. The term anticoccidial agent is to be preferred to describe all drugs with activity against coccidia. Salinomycin, Maduramycin, lasalocid, Clopidol, narasin, Monensin, etc.
Anticoccidial drugs are defined as a chemical agent which act on Emeria spp which is causing coccidiosis in poultry and others animals.
What is Coccidiosis
Coccidiosis is a protozoal disease caused by Eimeria species under the family of apicomplexan that affects mainly the intestinal tract of poultry. Bloody diarrhea is a common clinical sign of coccidiosis in poultry. There are seven active species that generally caused disease in poultry.
Types Of Anticoccidial Drugs
Numerous drugs have been approved for coccidiosis since 1948. It can be into classified three types according to their origin are given below-
- 1. Synthetic drugs
- 2. Polyether antibiotics or ionophores
- 3. Mixed Drugs
1. Synthetic drugs
It is defined as a compound produced in a laboratory rather than natural ingredients or product synthesis from chemicals. So it’s often referred to as chemicals. Its have an active mode of action against coccidial spp.
Dinitolmide ( zoaline)
Dequinate (methyl benzoate)
2. Polyether antibiotics or ionophores
Its define as natural & biologically active compounds/ substances produced by fermentation of streptomyces or actinomadura. It destroys Emeria spp by inferring balance od most important ion especially sodium & potassium.
Classified as two classes
a) Monovalent ionophores
Its define as Ionophoes that have valency one called Monovalent ionophores. eg monensin, narasin, and salinomycin & Monovalent glycosidic ionophores (maduramicin and semduramycin).
b) Divalent ionophores
Its define as Ionophoes that have valency two called Divalent ionophores eg lasalocid
3. Mixed Anticoccidial Drugs
Its define as a mixer of two or more anticoccidials drugs either synthetic & chemical origin.Eg Narasin+Nicarbazine etc